Blood sugar control is critical to the health of people with type 2 diabetes and prediabetes. Pendulum Therapeutics is a microbiome startup dedicated to improving people’s health by developing microbiome-targeted solutions.
What Is Pendulum?
Pendulum Therapeutics is the first and only evidence-based microbiome firm to use high-resolution, long-read DNA sequencing discoveries to develop and commercialize microbiome therapies for specific diseases.
Glucose Control,Akkermansia and GI Repair Program , these medical probiotics from Pendulum Therapeutics, were recently launched to assist treat type 2 diabetes & metabolic health.
According to some study, type 2 diabetes may be connected to a microbial imbalance in the stomach.
It appears that persons with type 2 diabetes have a finite number of good bacterial strains to aid in fiber digestion and the production of butyrate, a key chemical that helps to regulate insulin and glucose levels.
Pendulum Glucose Control
Pendulum Glucose Control, the company’s flagship product, is the only clinically proven Medical Probiotic, providing dietary management through a blend of five different probiotic strains and one prebiotic in the form of chicory inulin to help people with type 2 diabetes manage their A1C and blood sugar levels. Pendulum’s proprietary innovation platform allows for the quick identification of microbial mechanisms of action, as well as rapid translation from discovery to human clinical validation.
The product claims that its specific strains of helpful bacteria can help persons with type 2 diabetes balance and rebuild their gut microbiota, resulting in better blood sugar control.
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Pendulum Akkermansia
The probiotic strain Akkermansia muciniphila WB-STR-001 is named after Pendulum’s other product, Akkermansia. Chicory inulin, a prebiotic, is also found in Akkermansia.
The probiotic strain Akkermansia is vital for preserving your gut lining and can help avoid leaky gut syndrome. Inflammation, gastrointestinal problems, and even type 2 diabetes can all be caused by a leaky gut.
According to new research, low levels of Akkermansia in the GI tract can contribute to type 2 diabetes, and replenishing this good bacteria can help avoid the illness.
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Pendulum GI Repair Program
GI Repair is a potent probiotic that relieves gas, bloating, diarrhea, and constipation on a regular basis.
You have access to the GI Repair Program as part of your membership, which includes free dietary coaching and health surveys to help you find your unique answer.
The enteric-coated capsule from GI Relief is acid-resistant, which means it can make it through the stomach’s acidity, the small intestines, and into the large intestines to do its function. Butyrate acid is ineffective compared to our approach.
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John Eid, Jim Bullard, and Colleen Cutcliffe, who have substantial backgrounds in biophysics, computational biology, biostatistics, biochemistry, and molecular biology, developed Pendulum Therapeutics.
In addition to scientists and inventors, the company seeks advice from a variety of healthcare experts, including physicians and nurse practitioners.
Pendulum Glucose Control review
Pendulum Glucose Control was found to lower hemoglobin A1C and after-meal blood sugar increases in a recent clinical investigation.
To further understand the link between the gut microbiome and blood sugar control in persons with type 2 diabetes, more extensive and thorough research is required.
The probiotic strains in Glucose Control are a customized combination comprising the following:
- Akkermansia muciniphila WB-STR-0001, 1 billion AFUs
- Anaerobutyricum hallii WB-STR-0008, 1 billion AFUs
- Bifidobacterium infantis 100, 2 billion AFUs
- Clostridium beijerinckii WB-STR-0005, 3 billion AFUs
- Clostridium butyricum WB-STR-0006, 3 billion AFUs
Chicory inulin, a prebiotic, is also included in Glucose Control. The prebiotic acts as nourishment for the probiotic bacteria, increasing their effectiveness.
The British Medical Journal’s Open Diabetes Research & Care Journal just published a paper on Pendulum Glucose Control.
Researchers compared the effects of two distinct probiotic blends with placebo on blood sugar control in 76 people with type 2 diabetes in a 12-week double-blind clinical experiment.
In comparison to the placebo, Glucose Control lowered hemoglobin A1C by 0.6. Researchers also discovered that the product lowered blood sugar rises after meals by 32%.
Even though these findings are excellent, a 12-week trial with 76 individuals is limited in terms of duration and sample size.
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Akkermansia review
Only one probiotic, Akkermansia muciniphila WB-STR-001 (1 billion AFUs), and one prebiotic, chicory inulin, are found in Pendulum’s other product, Akkermansia.
The strain discovered in Glucose Control is Akkermansia muciniphila.
Reduced levels of Akkermansia muciniphila, a well-studied probiotic strain, have been associated to an increased risk of obesity.
Furthermore, research show that a lower level of Akkermansia muciniphila in the stomach is connected to prediabetes and type 2 diabetes.
There is mounting evidence that Akkermansia muciniphila may aid in the regulation of blood sugar in persons with type 2 diabetes.
This product’s prebiotic is designed to feed the probiotics and help them work more effectively.
Ingredients Analysis
Pendulum Akkermansia is available in capsule or powder form. A 30-day supply of both the capsules and the powder is available. Pendulum recommends taking one serving per day to help maintain your gut healthy and nurture your body’s flora. The capsules should be taken once a day with food for people who are utilizing them. You can take the powder once a day by dusting the recommended dosage over top of a soft food like yogurt or applesauce and immediately eating it.
Capsules of Akkermansia
- Oligofructose with Chicory Inulin
- Magnesium Stearate is a kind of magnesium salt.
- WB-STR-0001 Akkermansia muciniphila
- Hydroxypropyl Methylcellulose Phthalate, Hydroxypropyl Methylcellulose) Capsule (Water, Hydroxypropyl Methylcellulose Phthalate, Hydroxypropyl Methylcellulose)
Powder
- Oligofructose with Chicory Inulin
- Magnesium Stearate
- WB-STR-0001 Akkermansia muciniphila
The probiotic strain Akkermansia muciniphila has been extensively studied and has been shown to aid in the prevention of obesity and type 2 diabetes.
It may also aid in the management of blood sugar control in persons with type 2 diabetes.
Is it Worth Trying Pendulum Akkermansia?
In today’s world, Akkermansia is one of the most researched probiotic strains, and Pendulum has figured out a way to make it available to anyone who wants to improve their gut health.
For years, Pendulum has been a reliable source for people with type 2 diabetes, as its flagship product, Glucose Control, has been shown to help people with type 2 diabetes manage their A1C and blood glucose levels.
Pros
- Designed to help your body’s microbiome thrive.
- Pendulum is the only brand of probiotics that incorporates
- Akkermansia, which has been recognized as a keystone strain for gut health.
- Akkermansia has been extensively studied, and it has been documented in over 1,000 scientific articles.
Cons
- A 30-day supply will set you back slightly over $100.
- According to studies, you must continue to take it to sustain higher levels of Akkermansia in your body, therefore you must be willing to take it for the long haul to reap the full advantages.
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Pendulum Probiotics benefits
Based on the existing studies, the following is a summary of the available evidence for the stated benefits of Pendulum Probiotics:
- Aids in the reduction of A1c (Strong Evidence)
- Reduces blood glucose increases.(Strong Evidence)
- Promotes gastrointestinal health.(Strong Evidence)
- Increases metabolism (There isn’t much evidence)
Clinical studies on Pendulum’s Glucose Control found that the product reduced A1C levels and after-meal blood sugar rises.
The strains in the product are likely to aid with gut health, but the study was primarily focused on the product’s ability to help with blood sugar management.
Pendulum’s Akkermansia has been demonstrated to help persons with type 2 diabetes control their blood sugar levels and may even help avoid the disease.
The clinical trial conducted by Pendulum had a tiny sample size and lasted only 12 weeks. For both reducing A1C and lowering blood sugar spikes, a more thorough study would have warranted a 5-star rating.
While there’s a chance that Pendulum’s goods can help you lose weight, there’s very no clinical data to back this up.
Pendulum glucose control promo code
Side Effects, Safety, and Dosage
Pendulum’s Glucose Control recommends taking two capsules with food, one in the morning and one in the evening, according to the maker.
Take 1 capsule with food each day if you’re taking Pendulum’s Akkermansia. If you opt for the powdered version, you’ll pour one serving over a soft item like yogurt or applesauce and eat it right away.
Mild gastrointestinal symptoms such as nausea, loose stools, and diarrhea are possible adverse effects of both products during the first 3–5 days of administration.
Glucose Control is non-GMO, vegan, and free of all major allergies. It’s vital to remember that Glucose Control will be shipped cold and will need to be refrigerated right away.
Pendulum’s goods should only be used under medical supervision. Before making any modifications to your existing treatment plan or everyday routine, consult your doctor.
The Bottom Line
Pendulum has a variety of unique items that are validated by clinical research.
Pendulum Glucose Control is backed by their own clinical study, which revealed that this combination of probiotics and prebiotics was helpful in decreasing A1C readings and preventing blood sugar increases after meals.
Pendulum Akkermansia has the same probiotic (Akkermansia muciniphila) as their prebiotic.
The probiotic strain Akkermansia muciniphila has been extensively examined and may aid in the prevention of obesity and type 2 diabetes, as well as blood sugar regulation.
While both products are expensive, the evidence supporting their usefulness is compelling.
In addition, if you buy Glucose Control and select the subscription option, you’ll get free dietary advice and A1C tests.
Pendulum GI Repair is an effective probiotic that aids in the relief of occasional gas, bloating, diarrhea, and constipation.
You have access to the GI Repair Program as part of your membership, which includes free dietary counseling and health surveys to help you find your unique answer.
Pendulum Akkermansia is less expensive than others and may have similar benefits. If considering any of these products, Akkermansia appears to be a good starting place given its lower price point.
If you’re looking for something more comprehensive that may decrease A1C levels and lower after-meal blood sugar spikes, it may be worth considering Glucose Control. The product also comes with free resources to help you better manage your blood sugar levels.
If you have occasional stomach discomfort, a healthy, diversified gut microbiota is the key to symptom resolution. The GI Repair Program offers a holistic approach by developing customized formulas that target key pathways associated with GI discomfort.
The products are intended for use under medical supervision. You should speak with your physician before making any changes to your current treatment plan or medication regime.
FAQ
Do pendulum probiotics work?
The study shows that Pendulum’s unique probiotic strains can provide dietary management of blood glucose control through the gut microbiota, as well as clinically and statistically significant reductions in A1C and blood glucose spikes in persons with type 2 diabetes.
What is the best way to take a pendulum probiotic?
Pendulum Glucose Control should be taken on a daily basis.
Take 1 capsule with food in the morning and 1 capsule with food in the evening. If you miss a dose, you can catch up by taking two capsules the next time.
What goes into making a pendulum?
Pendulum Glucose Control is the only probiotic that has the combination of Akkermansia muciniphila, Clostridium beijerinckii, Clostridium butyricum, Bifidobacterium infantis, and Anaerobutyricum hallii, which aids in the maintenance of people’s own healthy microbiomes.
Is pendulum glucose control approved by the FDA?
According to the FDA and section 5(b) of the Orphan Drug Act, Pendulum Glucose Control is GRAS (generally regarded as safe) and sold as a medical food.
What is pendulum probiotics for type 2 diabetes?
Meet the only medicinal probiotic on the market for Type 2 diabetes control. A clinical investigation reveals that Pendulum Glucose Control reduces A1C levels and regulates after-meal blood-glucose rises in people with Type 2 diabetes who are taking metformin.
What are the components of pendulum glucose control?
Pendulum’s Glucose Control Formulation is made up of five human commensal bacteria strains that produce butyrate and degrade mucin. The organisms were cultivated under strict guidelines in accordance with Good Manufacturing Practices (GMP), and no animal-derived ingredients were used.
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